Article
MALDI-TOF mass spectrometry proteomic phenotyping of clinically relevant fungi.
Molecular bioSystems - 1 Mar 2011
Putignani Lorenza, Del Chierico Federica, Onori Manuela, Mancinelli Livia, Argentieri Marta, Bernaschi Paola, Coltella Luana, Lucignano Barbara, Pansani Laura, Ranno Stefania, Russo Cristina, Urbani Andrea, Federici Giorgio, Menichella Donato
Abstract excerpt
Proteomics is particularly suitable for characterising human pathogens with high life cycle complexity, such as fungi. Protein content and expression levels may be affected by growth states and life cycle morphs and correlate to species and strain variation. Identification and typing of fungi by conventional methods are often difficult, time-consuming and frequently, for unusual species, inconclusive. Proteomic...
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