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Article

Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance.

The Journal of biological chemistry - 24 Dec 2010

Mendoza-Cózatl David G, Zhai Zhiyang, Jobe Timothy O, Akmakjian Garo Z, Song Won-Yong, Limbo Oliver, Russell Matthew R, Kozlovskyy Volodymyr I, Martinoia Enrico, Vatamaniuk Olena K, Russell Paul, Schroeder Julian I

Abstract excerpt

Phytochelatins mediate tolerance to heavy metals in plants and some fungi by sequestering phytochelatin-metal complexes into vacuoles. To date, only Schizosaccharomyces pombe Hmt1 has been described as a phytochelatin transporter and attempts to identify orthologous phytochelatin transporters in plants and other organisms have failed. Furthermore, recent data indicate that the hmt1 mutant accumulates significant...

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PMID: 20937798
DOI: 10.1074/jbc.M110.155408
PMCID: PMC3003340

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