Article
A comparison of DNA sequencing and the hydrolysis probe analysis (TaqMan assay) for knockdown resistance (kdr) mutations in Anopheles gambiae from the Republic of the Congo.
Malaria journal - 12 Oct 2010
Choi Kwang Shik, Spillings Belinda L, Coetzee Maureen, Hunt Richard H, Koekemoer Lizette L
Abstract excerpt
BACKGROUND: Knockdown resistance (kdr) caused by a single base pair mutation in the sodium channel gene is strongly associated with pyrethroid insecticide resistance in Anopheles gambiae in West-Central Africa. Recently, various molecular techniques have been developed to screen for the presence of the kdr mutations in vector populations with varying levels of accuracy. In this study, the results of the...
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