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Article

Dent's disease: clinical features and molecular basis.

Pediatric nephrology (Berlin, Germany) - 1 May 2011

Claverie-Martín Félix, Ramos-Trujillo Elena, García-Nieto Víctor

Abstract excerpt

Dent's disease is an X-linked recessive renal tubulopathy characterized by low-molecular-weight proteinuria (LMWP), hypercalciuria, nephrocalcinosis, nephrolithiasis, and progressive renal failure. LMWP is the most constant feature, while the other clinical manifestations show wide variability. Patients also present variable manifestations of proximal tubule dysfunctions, such as aminoaciduria, glucosuria,...

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Identifiers

PMID: 20936522
DOI: 10.1007/s00467-010-1657-0

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CLCN5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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