Article
The role of brain-derived neurotrophic factor genotype, parental depression, and relationship discord in predicting early-emerging negative emotionality.
Psychological science - 1 Nov 2010
Hayden Elizabeth P, Klein Daniel N, Dougherty Lea R, Olino Thomas M, Dyson Margaret W, Durbin C Emily, Sheikh Haroon I, Singh Shiva M
Abstract excerpt
The brain-derived neurotrophic factor (BDNF) gene is a plausible candidate for early-emerging negative emotionality (NE), and evidence suggests that the effects of this gene may be especially salient in the context of familial risk for child maladjustment. We therefore examined whether the single-nucleotide polymorphism producing a valine-to-methionine substitution at codon 66 (val66met) of the BDNF gene was...
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