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Article

Evidence that familial liability for psychosis is expressed as differential sensitivity to cannabis: an analysis of patient-sibling and sibling-control pairs.

Archives of general psychiatry - 1 Feb 2011

Abstract excerpt

CONTEXT: Individual differences in cannabis sensitivity may be associated with genetic risk for psychotic disorder. OBJECTIVES: To demonstrate and replicate, using 2 conceptually different genetic epidemiological designs, that (familial) liability to psychosis is associated with sensitivity to cannabis. DESIGN, SETTING, AND PARTICIPANTS: Sibling-control and cross-sibling comparisons using samples of patients with...

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PMID: 20921112
DOI: 10.1001/archgenpsychiatry.2010.132

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