Article
[Use of quantitative fluorescence polymerase chain reaction in the invasive prenatal diagnosis of Down's syndrome].
Klinicheskaia laboratornaia diagnostika - 1 Aug 2010
Kriventsova N V, Shokarev R A, Avrutskaia V V, Kriger S Iu, Klochkova N E, Gimbut V S, Kornienko I V
Abstract excerpt
A quantitative fluorescence polymerase chain reaction (QF-PCR) technique based on the determination of triple-dose chromosome-specific short tandem repeats (STR) has been recently developed for the prenatal diagnosis of numeral abnormalities of chromosomes 21, 18, 13 and X and Y. This investigation examined 55 blood samples from healthy donors, 17 amniotic fluid samples, 27 blood samples from children with...
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