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Effect of ICSI on gene expression and development of mouse preimplantation embryos

1 Oct 2010

Abstract excerpt

BACKGROUND: In vitro culture (IVC) and IVF of preimplantation mouse embryos are associated with changes in gene expression. It is however not known whether ICSI has additional effects on the transcriptome of mouse blastocysts. METHODS: We compared gene expression and development of mouse blastocysts produced by ICSI and cultured in Whitten's medium (ICSI(WM)) or KSOM medium with amino acids (ICSI(KSOMaa)) with...

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PMID: 20889529
DOI: 10.1093/humrep/deq266

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