Article
No evidence that rare coding variants in ZNF804A confer risk of schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2010
Dwyer S, Williams H, Holmans P, Moskvina V, Craddock N, Owen M J, O'Donovan M C
Abstract excerpt
Strong evidence that rare variants of relatively high penetrance are involved in the etiology of schizophrenia is currently restricted to the data from studies investigating copy number variants and major structural re-arrangements in that disorder. Global tests of the hypothesis of the involvement of fairly high penetrance rare single nucleotide changes or small insertion deletion events await the genesis of...
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