Article
Adaptation of Staphylococcus aureus to ruminant and equine hosts involves SaPI-carried variants of von Willebrand factor-binding protein.
Molecular microbiology - 1 Sept 2010
Viana David, Blanco José, Tormo-Más María Angeles, Selva Laura, Guinane Caitriona M, Baselga Rafael, Corpa Juan M, Lasa Iñigo, Novick Richard P, Fitzgerald J Ross, Penadés José R
Abstract excerpt
Staphylococci adapt specifically to various animal hosts by genetically determined mechanisms that are not well understood. One such adaptation involves the ability to coagulate host plasma, by which strains isolated from ruminants or horses can be differentiated from closely related human strains. Here, we report first that this differential coagulation activity is due to animal-specific alleles of the von...
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