Article
Clinical disease caused by Klebsiella in 2 unrelated patients with interleukin 12 receptor beta1 deficiency.
Pediatrics - 1 Oct 2010
Pedraza Sigifredo, Lezana Jose Luis, Samarina Arina, Aldana Ruth, Herrera Maria Teresa, Boisson-Dupuis Stéphanie, Bustamante Jacinta, Pages Perle, Casanova Jean-Laurent, Picard Capucine
Abstract excerpt
Patients with interleukin 12 (IL-12)p40 or IL-12 receptor β1 (IL12Rβ1) deficiencies are prone to develop infections caused by mycobacteria and salmonella; other infections have only been rarely observed. In this report we describe 2 unrelated patients with complete autosomal recessive IL12Rβ1 deficiency who suffered from sepsis attributable to Klebsiella pneumoniae. A Mexican boy suffered from disseminated...
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