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DNA methylase modifications and other linezolid resistance mutations in coagulase-negative staphylococci in Italy

18 Sept 2010

Abstract excerpt

BACKGROUND: Despite 10 years of clinical use, linezolid resistance in Staphylococcus aureus and coagulase-negative staphylococci (CoNS) is still a rare phenomenon. This study reports the mechanisms of resistance and strain types seen in clusters of linezolid-resistant CoNS from two different hospitals in Italy during the period 2008-09. METHODS: Genes associated with linezolid resistance were subjected to...

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PMID: 20852270
DOI: 10.1093/jac/dkq344

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