Article
Total pancreatectomy and islet cell autotransplantation as a means of treating patients with genetically linked pancreatitis.
Surgery - 1 Oct 2010
Sutton Jeffrey M, Schmulewitz Nathan, Sussman Jeffrey J, Smith Milton, Kurland Jayde E, Brunner John E, Salehi Marzieh, Choe Kyuran A, Ahmad Syed A
Abstract excerpt
BACKGROUND: For patients with severe chronic pancreatitis, total or completion pancreatectomy with islet cell autotransplantation (IAT) can alleviate pain and avoid the complications of diabetes. Several genetic mutations, specifically, PRSS1, CFTR, and SPINK1, are associated with chronic pancreatitis. Few reports have focused on the benefit of this operation for this subset of patients. METHODS: Between February...
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