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Probing the pan-genome of Listeria monocytogenes: new insights into intraspecific niche expansion and genomic diversification.

BMC genomics - 16 Sept 2010

Deng Xiangyu, Phillippy Adam M, Li Zengxin, Salzberg Steven L, Zhang Wei

Abstract excerpt

BACKGROUND: Bacterial pathogens often show significant intraspecific variations in ecological fitness, host preference and pathogenic potential to cause infectious disease. The species of Listeria monocytogenes, a facultative intracellular pathogen and the causative agent of human listeriosis, consists of at least three distinct genetic lineages. Two of these lineages predominantly cause human sporadic and...

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PMID: 20846431
DOI: 10.1186/1471-2164-11-500
PMCID: PMC2996996

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