Article
High-throughput sequencing and clinical microbiology: progress, opportunities and challenges.
Current opinion in microbiology - 1 Oct 2010
Pallen Mark J, Loman Nicholas J, Penn Charles W
Abstract excerpt
High-throughput sequencing is sweeping through clinical microbiology, transforming our discipline in its wake. It is already providing an enhanced view of pathogen biology through rapid and inexpensive whole-genome sequencing and more sophisticated applications such as RNA-seq. It also promises to deliver high-resolution genomic epidemiology as the ultimate typing method for bacteria. However, the most...
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