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Non-invasive prenatal determination of fetal sex: translating research into clinical practice

20 Aug 2010

Abstract excerpt

The effectiveness and clinical utility of non-invasive prenatal diagnosis (NIPD) for fetal sex determination using cell-free fetal DNA (cffDNA) was assessed by undertaking a prospective national audit of UK testing. NIPD was performed using real-time polymerase chain reaction analysis of the DYS14 or SRY gene in cffDNA extracted from maternal plasma. All cases referred for fetal sex determination from 1 April...

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PMID: 20840219
DOI: 10.1111/j.1399-0004.2010.01533.x

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