Article
Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice.
Journal of bone and mineral metabolism - 1 May 2011
Hanagata Nobutaka, Li Xianglan, Morita Hiromi, Takemura Taro, Li Jie, Minowa Takashi
Abstract excerpt
Interferon-inducible transmembrane protein 5 (IFITM5) is an osteoblast-specific membrane protein whose expression peaks around the early mineralization stage during the osteoblast maturation process. To investigate IFITM5 function, we first sought to identify which proteins interact with IFITM5. Liquid chromatography mass spectrometry revealed that FK506-binding protein 11 (FKBP11) co-immunoprecipitated with...
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