Article
Genome analysis of Legionella ssp. by orthogonal field alternation gel electrophoresis (OFAGE).
FEMS microbiology letters - 1 Nov 1990
Bender L, Ott M, Marre R, Hacker J
Abstract excerpt
Various Legionella isolates from different sources and origins were analysed by orthogonal field alternation gel electrophoresis of NotI cleaved genomic DNA. The genome of L. pneumophila Philadelphia I, the original isolate of the epidemics in 1976, exhibits only five NotI fragments. Two virulent derivatives, derived from L. pneumophila Philadelphia I, which were obtained by prolonged passage on artificial...
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