Article
Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations.
Lung cancer (Amsterdam, Netherlands) - 1 May 2011
Wu Jenn-Yu, Wu Shang-Gin, Yang Chih-Hsin, Chang Yih-Leong, Chang Yeun-Chung, Hsu Ya-Chieh, Shih Jin-Yuan, Yang Pan-Chyr
Abstract excerpt
INTRODUCTION: Erlotinib and gefitinib are tyrosine kinase (TK) inhibitors of epidermal growth factor receptor (EGFR) that are effective in treating non-small cell lung cancer (NSCLC). This study aimed to compare their clinical uses and the influence of EGFR mutation. METHODS: The usages of erlotinib and gefitinib in advanced NSCLC were analyzed. Clinical data and EGFR mutational status of tumors were collected....
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