Article
ADRB2 haplotype is associated with glucose tolerance and insulin sensitivity in obese postmenopausal women.
Obesity (Silver Spring, Md.) - 1 Feb 2011
Prior Steven J, Goldberg Andrew P, Ryan Alice S
Abstract excerpt
The β(2)-adrenergic receptor (ADRB2) mediates obesity, cardiorespiratory fitness, and insulin resistance. We examined the hypothesis that ADRB2 Arg16Gly-Gln27Glu haplotype is associated with body composition, glucose tolerance, and insulin sensitivity in obese, postmenopausal women. Obese (>35% body fat), postmenopausal (age 45-75 years) women (n = 123) underwent genotyping, dual-energy X-ray absorptiometry, and...
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