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Article

Emergent cooperation in microbial metabolism.

Molecular systems biology - 7 Sept 2010

Wintermute Edwin H, Silver Pamela A

Abstract excerpt

Mixed microbial communities exhibit emergent biochemical properties not found in clonal monocultures. We report a new type of synthetic genetic interaction, synthetic mutualism in trans (SMIT), in which certain pairs of auxotrophic Escherichia coli mutants complement one another's growth by cross-feeding essential metabolites. We find significant metabolic synergy in 17% of 1035 such pairs tested, with SMIT...

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Identifiers

PMID: 20823845
DOI: 10.1038/msb.2010.66
PMCID: PMC2964121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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