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Article

Proteasome inhibition induces developmentally deregulated programs of apoptotic and autophagic cell death during Drosophila melanogaster oogenesis.

Cell biology international - 1 Jan 2011

Velentzas Panagiotis D, Velentzas Athanassios D, Mpakou Vassiliki E, Papassideri Issidora S, Stravopodis Dimitrios J, Margaritis Lukas H

Abstract excerpt

Ubiquitin/proteasome-mediated degradation of eukaryotic proteins is critically implicated in a number of signalling pathways and cellular processes. To specifically impair proteasome activities, in vitro developing Drosophila melanogaster egg chambers were exposed to the MG132 or epoxomicin proteasome inhibitors, while a GAL4/UAS binary genetic system was employed to generate double transgenic flies...

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Identifiers

PMID: 20819072
DOI: 10.1042/CBI20100191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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