Article
Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates.
FEBS letters - 24 Sept 2010
Chu Hsing-Mao, Chen Feng-Yuan, Ko Tzu-Ping, Wang Andrew H-J
Abstract excerpt
Various plant developmental processes involve phytohormones such as cytokinins. Isopentenyltransferase (IPT) reaction is the key rate-limiting step in cytokinin biosynthesis that transfers the isopentenyl (iP) group from dimethylallyl diphosphate to the N6-amino group of adenine. Here, a series of diadenosine polyphosphates (Ap(n)A) were screened as possible substrates of IPT, among which diadenosine...
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