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Article

Hypodysfibrinogenaemia due to production of mutant fibrinogen alpha-chains lacking fibrinopeptide A and polymerisation knob 'A'.

Thrombosis and haemostasis - 1 Nov 2010

Vorjohann Silja, Fish Richard J, Biron-Andréani Christine, Nagaswami Chandrasekaran, Weisel John W, Boulot Pierre, Reyftmann Lionel, de Moerloose Philippe, Neerman-Arbez Marguerite

Abstract excerpt

Inherited disorders of fibrinogen are rare and affect either the quantity (hypofibrinogenaemia and afibrinogenaemia) or the quality of the circulating fibrinogen (dysfibrinogenaemia) or both (hypodysfibrinogenaemia). Extensive allelic heterogeneity has been found for all these disorders: in congenital afibrinogenaemia for example more than 40 mutations, the majority in FGA , have been identified in homozygosity...

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Source

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Identifiers

PMID: 20806111
DOI: 10.1160/TH10-03-0161
PMCID: PMC3090204

Genes

FGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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