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Article

Impact of the AHI1 gene on the vulnerability to schizophrenia: a case-control association study.

PloS one - 18 Aug 2010

Rivero Olga, Reif Andreas, Sanjuán Julio, Moltó María D, Kittel-Schneider Sarah, Nájera Carmen, Töpner Theresia, Lesch Klaus-Peter

Abstract excerpt

BACKGROUND: The Abelson helper integration-1 (AHI1) gene is required for both cerebellar and cortical development in humans. While the accelerated evolution of AHI1 in the human lineage indicates a role in cognitive (dys)function, a linkage scan in large pedigrees identified AHI1 as a positional candidate for schizophrenia. To further investigate the contribution of AHI1 to the susceptibility of schizophrenia, we...

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Source

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Identifiers

PMID: 20805890
DOI: 10.1371/journal.pone.0012254
PMCID: PMC2923617

Genes

AHI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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