Article
Successful isolated liver transplantation in a child with atypical hemolytic uremic syndrome and a mutation in complement factor H.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Sept 2010
Haller W, Milford D V, Goodship T H J, Sharif K, Mirza D F, McKiernan P J
Abstract excerpt
A male infant was diagnosed with atypical hemolytic uremic syndrome (aHUS) at the age of 5.5 months. Sequencing of the gene (CFH) encoding complement factor H revealed a heterozygous mutation (c.3644G>A, p.Arg1215Gln). Despite maintenance plasmapheresis he developed recurrent episodes of aHUS and vascular access complications while maintaining stable renal function. At the age of 5 years he received an isolated...
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