Article
Transplantation in atypical hemolytic uremic syndrome.
Seminars in thrombosis and hemostasis - 1 Sept 2010
Kavanagh David, Richards Anna, Goodship Tim, Jalanko Hannu
Abstract excerpt
Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by overactivation of complement. Recurrence following renal transplantation is determined by a genetic predisposition. Genetic screening of all individuals with aHUS should be performed prior to listing for transplantation. Individuals with isolated mutations in MCP have a low risk of recurrence and may be considered for kidney transplantation...
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