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The convergence of therapeutic drug monitoring and pharmacogenetic testing to optimize efavirenz therapy.

Therapeutic drug monitoring - 1 Oct 2010

Cabrera Figueroa Salvador, Fernández de Gatta María, Hernández García Lorena, Domínguez-Gil Hurlé Alfonso, Bustos Bernal Carmen, Sepúlveda Correa Rosa, García Sánchez María José

Abstract excerpt

The aim of this study was to show the benefits of combining therapeutic drug monitoring (TDM) and pharmacogenetic analyses to optimize efavirenz (EFV) therapy. Patients were selected to minimize nongenetic differences between patients: 32 HIV adherent patients without drug interactions treated with an EFV nonindividualized dose over at least 1 year and included in a TDM program were genotyped according to minimum...

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PMID: 20720517
DOI: 10.1097/FTD.0b013e3181f0634c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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