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Article

PGD for fragile X syndrome: ovarian function is the main determinant of success.

Human reproduction (Oxford, England) - 1 Oct 2010

Tsafrir Avi, Altarescu Gheona, Margalioth Ehud, Brooks Baruch, Renbaum Paul, Levy-Lahad Ephrat, Rabinowitz Ron, Varshaver Irit, Eldar-Geva Talia

Abstract excerpt

BACKGROUND: PGD for fragile X syndrome (FRAX) is inefficient, probably owing to fewer oocytes, poor embryo quality and difficulties in genetic analysis. We investigated IVF-PGD in FRAX mutation carriers compared with controls, looking at the effects of oocyte and embryo number/quality on live bir...

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Source

Identifiers

PMID: 20713414
DOI: 10.1093/humrep/deq203

Genes

PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20713414-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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