Article
Transmission of drug-resistant HIV type 1 strains in HAART-naive patients: a 5-year retrospective study in Sicily, Italy.
AIDS research and human retroviruses - 1 Sept 2010
Bonura Filippa, Tramuto Fabio, Vitale Francesco, Perna Anna Maria, Viviano Enza, Romano Nino
Abstract excerpt
The transmission of drug-resistant HIV-1 strains might compromise the efficacy of current first-line antiretroviral (ARV) regimens. Between 2004 and 2008, HIV-1 reverse transcriptase (RT) and protease (PR) genes of 108 ARV-naive Sicilian patients were amplified and sequenced to describe the prevalence of ARV resistance mutations among HAART-naive HIV-1-infected individuals. The frequency of transmitted drug...
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