Article
The expression of CD22 (Leu 14) and CD11c (LeuM5) in chronic lymphoproliferative disorders using two-color flow cytometric analysis.
American journal of clinical pathology - 1 Jul 1991
Miller M L, Fishleder A J, Tubbs R R
Abstract excerpt
The monoclonal antibodies (MoAbs) CD22 and CD11c recognize B-lymphocyte- and monocyte-associated antigens, respectively. Reports indicate that when these two MoAbs co-express, they represent a unique marker for hairy cell leukemia (HCL) although neither is specific for that disease. The authors evaluated the expression and diagnostic utility of CD22 and CD11C in specimens from 26 normal subjects, 29 patients,...
Topics
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- Cell Adhesion Molecules
- Chronic Disease
- Color
- Flow Cytometry
- Fluorescent Antibody Technique
- HLA-DR Antigens
- Humans
- Integrin alphaXbeta2