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Article

Heterogeneity in the sensitivity of stocks and clones of Giardia to metronidazole and ornidazole.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jan 2000

Majewska A C, Kasprzak W, De Jonckheere J F, Kaczmarek E

Abstract excerpt

The sensitivity in vitro to metronidazole and ornidazole of 7 stocks and of the cloned lines of 5 stocks of Giardia isolated from humans, rodents and monkeys was studied by the growth inhibition test. All 7 stocks of Giardia, irrespective of the host, differed in their sensitivity to these drugs, commonly used in therapy of human giardiasis. The differences were greater with ornidazole than with metronidazole....

Topics

Animals
Drug Resistance
Genetic Variation
Giardia
Heterozygote
Metronidazole
Ornidazole

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2068765
DOI: 10.1016/0035-9203(91)90161-q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2068765-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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