Article
Power and false-positive rate in QTL detection with near-isogenic line libraries.
Heredity - 1 Apr 2011
Falke K C, Frisch M
Abstract excerpt
Libraries of near-isogenic lines (NILs) were used for quantitative trait locus (QTL) detection in model species and economically important crops. The experimental design and genetic architecture of the considered traits determine the statistical properties of QTL detection. The objectives of our simulation study were to (i) investigate the population sizes required to develop NIL libraries in barley and maize,...
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