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Article

Drug discovery in a multidimensional world: systems, patterns, and networks.

Journal of cardiovascular translational research - 1 Oct 2010

Dudley Joel T, Schadt Eric, Sirota Marina, Butte Atul J, Ashley Euan

Abstract excerpt

Despite great strides in revealing and understanding the physiological and molecular bases of cardiovascular disease, efforts to translate this understanding into needed therapeutic interventions continue to lag far behind the initial discoveries. Although pharmaceutical companies continue to increase investments into research and development, the number of drugs gaining federal approval is in decline. Many...

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PMID: 20677029
DOI: 10.1007/s12265-010-9214-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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