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Article

Genetic Association Studies of Antioxidant Pathway Genes and Schizophrenia

2 Aug 2010

Abstract excerpt

The endogenous production of highly reactive oxidation species is an inherent by-product of cellular energy metabolism. Cellular antioxidant defense systems (AODS) comprising various antioxidants counter these damaging effects. Several lines of evidence, including postmortem studies, suggest increased oxidative stress in patients with schizophrenia. Some genetic association studies and gene-expression studies...

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Identifiers

PMID: 20673164
DOI: 10.1089/ars.2010.3508

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