Article
Locus-specific database domain and data content analysis: evolution and content maturation toward clinical use.
Human mutation - 1 Oct 2010
Mitropoulou Christina, Webb Adam J, Mitropoulos Konstantinos, Brookes Anthony J, Patrinos George P
Abstract excerpt
Genetic variation databases have become indispensable in many areas of health care. In addition, more and more experts are depositing published and unpublished disease-causing variants of particular genes into locus-specific databases (LSDBs). Some of these databases contain such extensive information that they have become known as knowledge bases. Here, we analyzed 1,188 LSDBs and their content for the presence...
Topics
- Data Collection
- Database Management Systems
- Databases, Genetic
- Genes
- Genetic Diseases, Inborn
- Genetic Variation
- Humans
- Neoplasms
- Proteins