Article
[Immunogenotypic and clonal culture studies in Philadelphia chromosome-positive acute leukemia].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Apr 1991
Ohyashiki J H, Tauchi T, Ohyashiki K, Toyama K, Miyauchi J
Abstract excerpt
Molecular analysis and blast colony assay were performed on patients with Philadelphia chromosome-positive acute leukemia (Ph+ AL). All patients were diagnosed as ALL- L2 and 3 were My+ ALL. Nine of the 12 cases had rearranged immunoglobulin heavy chain, and 4 had rearranged TCR beta. TCR gamma rearrangement was noted in 3 patients, and TCR delta involvement was also noted in 6 patients. Clonal culture analysis...
Topics
- Acute Disease
- Adult
- Aged
- Female
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Gene Rearrangement, T-Lymphocyte
- Genotype
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Male
- Middle Aged