Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High frequency of migraine-only patients negative for the 3243 A>G tRNALeu mtDNA mutation in two MELAS families.

Cephalalgia : an international journal of headache - 1 Aug 2010

Cevoli Sabina, Pallotti Francesco, La Morgia Chiara, Valentino Maria L, Pierangeli Giulia, Cortelli Pietro, Baruzzi Agostino, Montagna Pasquale, Carelli Valerio

Abstract excerpt

Migraine is associated with stroke-like episodes in mitochondrial encephalomyopathy, lactic acidosis, stroke-like syndrome (MELAS). Moreover, abnormalities of oxidative phosphorylation are also reported in migraine. We studied two maternal lineages with MELAS and chronic progressive external ophthalmoplegia (CPEO) affected probands carrying the 3243 A>G tRNA(Leu) (MELAS) mutation, remarkable for a high frequency...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to MELAS Syndrome

Share to Migraine Disorders

Share to Pedigree

Share to Polymerase Chain Reaction

Share to RNA, Transfer, Leu

Source

Identifiers

PMID: 20656703
DOI: 10.1177/0333102409354654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High frequency of migraine-only patients negative for the 3243 A>G tRNALeu mtDNA mutation in two MELAS families.PMID 20656703Read ↗

Epidemiology of A3243G, the mutation for mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes: prevalence of the mutation in an adult population.Semantic proximity Read ↗

Frequency of MELAS main mutation in a phenotype-targeted young ischemic stroke patient population.Semantic proximity Read ↗

Contribution of nuclear and mitochondrial gene mutations in mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome.Semantic proximity Read ↗

Assessing the relative incidence of mitochondrial DNA A3243G in migraine without aura with maternal inheritance.Semantic proximity Read ↗

The m.3243A>G mitochondrial DNA mutation and related phenotypes. A matter of gender?Semantic proximity Read ↗

MELAS: clinical features, biochemistry, and molecular genetics.Semantic proximity Read ↗

Clinical features of MELAS and mitochondrial DNA mutations.Semantic proximity Read ↗

Current perspectives on mitochondrial dysfunction in migraine.Semantic proximity Read ↗

Ischemic optic neuropathy as first presentation in patient with m.3243 A > G MELAS classic mutation.Semantic proximity Read ↗

The syndrome of mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes presenting without stroke.Semantic proximity Read ↗

A whole mitochondrial genome screening in a MELAS patient: a novel mitochondrial tRNA(Val) mutation.Semantic proximity Read ↗

Diagnosis and management of MELAS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.