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Biological safety of human skin-derived stem cells after long-term in vitro culture

22 Jul 2010

Abstract excerpt

The aim of this study was to investigate the biological safety of human skin-derived mesenchymal stem cells (HSMSCs) cultured in vitro by detecting changes in karyotype, major histocompatibility complex expression and tumorigenicity. Before the 21st passage of the in vitro culture, cell surface markers were analysed by flow cytometry; major histocompatibility complex expression was detected by RT-PCR and flow...

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PMID: 20652875
DOI: 10.1002/term.290

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