Article
Polyethylenimine-mediated gene delivery into human bone marrow mesenchymal stem cells from patients.
Journal of cellular and molecular medicine - 1 Sept 2011
Wang Weiwei, Li Wenzhong, Ou Lailiang, Flick Eva, Mark Peter, Nesselmann Catharina, Lux Cornelia A, Gatzen Hans-Heinrich, Kaminski Alexander, Liebold Andreas, Lützow Karola, Lendlein Andreas, Li Ren-Ke, Steinhoff Gustav, Ma Nan
Abstract excerpt
Transplantation of mesenchymal stem cells (MSCs) derived from adult bone marrow has been proposed as a potential therapeutic approach for post-infarction left ventricular (LV) dysfunction. However, age-related functional decline of stem cells has restricted their clinical benefits after transplantation into the infarcted myocardium. The limitations imposed on patient cells could be addressed by genetic...
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