Article
Chromosomal abnormalities in transformed Ph-negative myeloproliferative neoplasms are associated to the transformation subtype and independent of JAK2 and the TET2 mutations.
Genes, chromosomes & cancer - 1 Oct 2010
Nguyen-Khac Florence, Lesty Claude, Eclache Virginie, Couronné Lucile, Kosmider Olivier, Andrieux Joris, Collonge-Rame Marie-Agnes, Penther Dominique, Lafage Marina, Bilhou-Nabera Chrystele, Chapiro Elise, Mozziconacci Marie-Joelle, Mugneret Francine, Gachard Nathalie, Nadal Nathalie, Lippert Eric, Struski Stephanie, Dastugue Nicole, Cabrol Christine, Bernard Olivier A
Abstract excerpt
Evolution to myelofibrosis (MF), acute myeloid leukemia or myelodysplastic syndrome (AML/MDS) may occur over time in myeloproliferative neoplasms (MPN) patients most likely due to the acquisition of additional mutations. The Groupe Francophone de cytogenetique hematologique (GFCH) has collected a...
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