Article
Age-related changes in sleep in inbred mice are genotype dependent.
Neurobiology of aging - 1 Jan 2012
Hasan Sibah, Dauvilliers Yves, Mongrain Valérie, Franken Paul, Tafti Mehdi
Abstract excerpt
Aging produces major changes in sleep structure and intensity which might be linked to cognitive impairment in the elderly. In this study, the genetic contribution to age-related changes in sleep was assessed in three inbred mouse strains of various ages. Baseline sleep and the response to 6 hours sleep deprivation (SD) achieved by gentle handling were quantified in young, middle-aged, and older male mice using...
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