Article
A high prevalence of resistance in new tuberculosis cases of midwestern Brazil.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2010
Santos Lorena Cristina, Bousquet Hesther de Macedo, Pereira Alyne Melo, Junqueira-Kipnis Ana Paula, Kipnis André
Abstract excerpt
Tuberculosis (TB) is a serious worldwide public health problem, and drug resistance, particularly multidrug resistance (MDR), is a critical factor involved in TB control. We analyzed Mycobacterium tuberculosis isolates from 132 new TB cases of treatment-naïve patients in Goiás, Brazil by drug susceptibility tests, partial sequencing of the rpoB and katG genes, inhA(C-15T) mutation analysis by PCR, and RFLP-IS6110...
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