Article
Structure-based annotation of a novel sugar isomerase from the pathogenic E. coli O157:H7.
Journal of molecular biology - 3 Sept 2010
van Staalduinen Laura M, Park Chang-Su, Yeom Soo-Jin, Adams-Cioaba Melanie A, Oh Deok-Kun, Jia Zongchao
Abstract excerpt
Prokaryotes can use a variety of sugars as carbon sources in order to provide a selective survival advantage. The gene z5688 found in the pathogenic Escherichia coli O157:H7 encodes a "hypothetical" protein of unknown function. Sequence analysis identified the gene product as a putative member of the cupin superfamily of proteins, but no other functional information was known. We have determined the crystal...
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