Article
[The receptor theory of atherosclerosis].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 2010
Likhoded V G, Bondarenko V M, Gintsburg A L
Abstract excerpt
Lipopolysaccharides of Gram-negative bacteria can interact with Toll-like receptor 4 (TLR4) and induce atheroma formation. The risk of atherosclerosis is decreased in case of TLR4 mutation. Other bacterial ligands and endogenous ligands of TLRs can also be involved in induction of atherogenesis. The general concept of atherosclerosis pathogentsis is presented. According to this concept atherogenesis can be...
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