Article
Mapping candidate regions and genes for congenital anomalies of the kidneys and urinary tract (CAKUT) by array-based comparative genomic hybridization.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 2011
Weber Stefanie, Landwehr Christina, Renkert Miriam, Hoischen Alexander, Wühl Elke, Denecke Jonas, Radlwimmer Bernhard, Haffner Dieter, Schaefer Franz, Weber Ruthild G
Abstract excerpt
BACKGROUND: Congenital anomalies of the kidneys and urinary tract (CAKUT) are frequently associated with malformations of other organs. METHODS: In order to explore the role of DNA microimbalances in syndromal CAKUT, we applied genome-wide array-based comparative genomic hybridization (array-CGH) in 30 children with various CAKUT phenotypes and at least one additional extrarenal symptom. RESULTS: In three...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.