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Article

Hind limb unloading of mice modulates gene expression at the protein and mRNA level in mesenchymal bone cells

5 Jul 2010

Abstract excerpt

BACKGROUND: We investigated the extent, modalities and reversibility of changes at cellular level in the expression of genes and proteins occurring upon Hind limb unloading (HU) in the tibiae of young C57BL/6J male mice. We focused on the effects of HU in chondrogenic, osteogenic, and marrow mesenchymal cells. METHODS: We analyzed for expression of genes and proteins at two time points after HU (7 and 14 days),...

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PMID: 20602768
DOI: 10.1186/1471-2474-11-147

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