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Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

23 Jun 2010

Abstract excerpt

To identify molecularly defined subgroups in multiple myeloma, gene expression profiling was performed on purified CD138(+) plasma cells of 320 newly diagnosed myeloma patients included in the Dutch-Belgian/German HOVON-65/GMMG-HD4 trial. Hierarchical clustering identified 10 subgroups; 6 corresponded to clusters described in the University of Arkansas for Medical Science (UAMS) classification, CD-1 (n = 13,...

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PMID: 20574050
DOI: 10.1182/blood-2009-12-261032

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