Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI

23 Jun 2010

Abstract excerpt

BACKGROUND: HIV-1 is usually transmitted in the presence of semen. We have shown that semen boosts HIV-1 infection and contains fragments of prostatic acid phosphatase (PAP) forming amyloid aggregates termed SEVI (semen-derived enhancer of viral infection) that promote virion attachment to target cells. Despite its importance for the global spread of HIV-1, however, the effect of semen on virus infection is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to interferon and immune responses
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20573198
DOI: 10.1186/1742-4690-7-55

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVIPMID 20573198Read ↗

The Surprising Role of Amyloid Fibrils in HIV InfectionSemantic proximity Read ↗

Seminal Plasma and Semen Amyloids Enhance Cytomegalovirus Infection in Cell CultureSemantic proximity Read ↗

Characterization of the Influence of Semen-Derived Enhancer of Virus Infection on the Interaction of HIV-1 with Female Reproductive Tract TissuesSemantic proximity Read ↗

Semen-Derived Amyloid Fibrils Drastically Enhance HIV InfectionSemantic proximity Read ↗

Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate CancerSemantic proximity Read ↗

Role of Semen in HIV‐1 Transmission: Inhibitor or facilitator?Semantic proximity Read ↗

Semen Protects CD4+ Target Cells from HIV Infection but Promotes the Preferential Transmission of R5 Tropic HIVSemantic proximity Read ↗

Human semen contains exosomes with potent anti-HIV-1 activitySemantic proximity Read ↗

Sperm can act as vectors for HIV‐1 transmission into vaginal and cervical epithelial cellsSemantic proximity Read ↗

Detection and biologic characterization of infectious HIV-1 in semen of seropositive men.Semantic proximity Read ↗

The role of semen in sexual transmission of HIV: beyond a carrier for virus particlesSemantic proximity Read ↗

Semen amyloids participate in spermatozoa selection and clearanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.