Article
MUT-TP53 2.0: a novel versatile matrix for statistical analysis of TP53 mutations in human cancer.
Human mutation - 1 Sept 2010
Soussi Thierry, Hamroun Dalil, Hjortsberg Linn, Rubio-Nevado Jean Michel, Fournier Jean Louis, Béroud Christophe
Abstract excerpt
Analysis of the literature reporting p53 mutations shows that 8% of report display typographical mistakes with a notable increase in recent years. These errors are sometimes isolated, but in some cases, they concern several or even all mutations described in a single article. Furthermore, some works report unusual profile of p53 mutations whose accuracy is difficult to assess. To handle these problems we have...
Topics
- Computational Biology
- Databases, Genetic
- Humans
- Meta-Analysis as Topic
- Mutant Proteins
- Mutation
- Neoplasms
- Software
- Statistics as Topic
- Tumor Suppressor Protein p53